The gold recovery is low in the flotation of a certain gold ore by conventional technique because of gold-bearing mineral in the ore is dispersed and their particle size are very fine.So,flotation experiment on the gold ore was carried out,in which fine grinding process was used and dispersant,collector Mac-12 were added.The experimental results showed that this flotation process is better adaptive to the gold ore,when pH=9 the gold recovery can be increased by 8.27% and the gold grade in concentrate can be increased by 21.28 g/t.