The negative influences of acidity waste water in copper mine were investigated. The adaptability of clay-solidified grouting curtain applied into the seepage prevent of dam foundation of the acidity water reservoir was analyzed.The application in the actual engineering of some mine shows that the stratum interspaces can be effectively filled with the clay-solidified grouts and the permeability coefficient of the stratum can be reduced by clay-solidified grouting technology and the acidity water is controlled and blocked up.