Five mining schemes are proposed based on the mining technological conditions of the deep orebody in Fankou Lead Zinc Mine. After a comparison of technical and economical indices and considering the current mining equipment and mining technology in the mine, the panel mechanized high slice cut-and-fill mining method is recommended to be tested and adopted for mining the deep orebody, with a reference to experiences of similar foreign mines, in order to achieve the targets of high efficiency, low cost and safety.