Since calcium magnesium minerals have obvious inhibiging effect on sulphide oxidization ore bodies containing calcium magnesium minerals in hanging wall andfootwall or sulphide ore associated with calcium magnesium minerals are not prone to spotaneous combustion. The inhibition mechanism of calcium magnesium minerals against sulphide ore spotaneous combustion were intensively experimented, leading to the conclusion that cement grout can be used to preven and extinguish sulphide related mine fires.