Contact of amonium nitrate in explosive with sulphide ore in high sulphur hot deposit tends to cause spontaneous combustion and detonation thre ate ning production safety. Addition of inhibitors into explosives may inhibit contact reaction. Selection of inhibitors, and the inhibition mechanism are described along with explosive formulation and preparation technology. As to the GLW safe iexplosive resistant to high sulfur and high temperature deto-naton performances, safety and storage life, and industrial blasting experiment are presented in the paper.