A copper-cobalt ore in Congo contains 2.47% Cu and 0.237% Co, which belongs to the ore with high oxidation rate and complex mineral composition. Aiming at the problems of high cost and low recovery rate of single flotation, flotation and magnetic separation combined process was used to carry out beneficiation tests according to ore properties. The results showed that easily beneficiated copper sulfide concentrate, copper oxide concentrate and cobalt concentrate could be selected by stepwise vulcanization flotation under the condition that the grinding particle size accounted for 70% of -0.074mm. The copper and cobalt minerals in the flotation tailings were recovered by strong magnetic separation, and the comprehensive copper recovery rate was 79.83% and cobalt recovery rate was 54.79%. The recovery rate of copper and cobalt was greatly improved, and the comprehensive and efficient utilization of resources was realized.