Aiming at the problems that may come along after through connection of east and west mining area in Liuzhuang Coal Mine,such as the interaction of fans,short air quantity of coal face and airflow disturbance in local area,the ventilation under four statuses before and after the cut - through of the railway transportation roadway was simulated and analyzed by computer. The results showed that after the cut - through there was great interaction between two main fans,if the return airway will be not controlled,the air quantity of coal face is short in east mining area and airflow disturbance occurs in local area of the west mining area. According to the simulation results,a permanent damper was set in the west of pedestrian association lane before thecut - through in time. After implementation of airflow control plan,the field measured results were almost consistent with the simulated results.