A polymetallic molybdenum ore with low sulfur content associated with low-grade bismuth and tungsten minerals.For making comprehensive recovery of the bismuth and tungsten resources,by the in-depth analysis on the properties of the run-of-mine ore and the tests,a flotation process of Mo-Bi bulk flotation separation and tailings bulk flotation followed by scheelite flotation was determined.The small-scale closed circuit test was conducted,and a molybdenum concentrate with Mo 52.42% and Mo recovery 95.11%,a bismuth concentrate with Bi 15.16% and Bi recovery 53.06%,and a scheelite concentrate with WO3 30.5% and WO3 recovery 36.60% were obtained.The result of research laid a technical foundation for the raising the comprehensive utilization ratio of mineral resources in the mine.