This paper introduces the several applications of micro-seismic monitoring technology in mine safety management,with the emphasis on the establishment and use of multi-channel and digital micro-seismic monitoring system in Fankou Lead-zinc Mine.The component and monitoring area and function of this system are explained in details.The high precision of vibrating source location of this system was validated through artificial vibrating source caused by blasting.This system is very important for improving the hazard monitoring and the safety management level of Chinese mines.