In the process of slicing mining of thick coal seam, the mining of upper slicing affects the layout of mining gateway on the working face of lower slicing. In order to determine the layout of gateway of lower slice at 110502 working face of Wangwa Coal Mine, the influence of upper slice coal pillar and goaf on lower slice was studied by combining the research method of field investigation, theoretical analysis and field test, and the technical scheme of narrow coal pillar along the goaf in the lower slice gateway was determined. The width of narrow coal pillar and gateway support parameters were designed, and the research results were applied to the driving operation of 110502 (2) tail gateway. The results show that the test gateway surrounding rock has a good control effect, which provides a theoretical and application basis for the follow-up narrow coal pillar goaf excavation in Wangwa Coal Mine.